A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

May 27, 2022

Primary Completion Date

December 26, 2023

Study Completion Date

November 30, 2025

Conditions
Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer
Interventions
DRUG

Lorlatinib

Dosage Form: Lorlatinib tablet, Dosage: 25mg/tablet, Dosing Regimens: 100mg, oral, Quaque Die (QD), continuous administration in 21 days as a cycle

Trial Locations (31)

510080

Guangdong Provincial People's hospital, Guangzhou

Unknown

Beijing Cancer Hospital, Beijing

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

The First Hospital of Jilin University, Changchun

Hunan Cancer Hospital, Changsha

Sichuan Cancer Hospital & Institute, Chengdu

West China Hospital of Sichuan University, Chengdu

Chinese PLA Army Medical Center, Chongqing

Fujian Cancer Hospital, Fuzhou

Sun Yat-sen University Cancer Center, Guangzhou

The first Affiliated hospital, Sun Yat-Sen University, Guangzhou

Zhejiang Cancer Hospital, Hangzhou

Harbin Medical University Cancer Hospital, Harbin

The First Affiliated Hospital of Anhui Medical University, Hefei

Shandong Cancer Hospital&Institute, Jinan

Yunnan Cancer Hospital, Kunming

The First Affiliated Hospital of Nanchang University, Nanchang

The Second Affiliated Hospital of Nanchang University, Nanchang

Jiangsu Province Hospital, Nanjing

Fudan University Shanghai Cancer Center, Shanghai

Shanghai Pulmonary Hospital, Shanghai

Liaoning Cancer Hospital and Institute, Shenyang

Shanxi Cancer hospital, Taiyuan

Tianjin Medical University Cancer Institute & Hospital, Tianjin

The 1st Affiliated hospital of Wenzhou Medical University, Wenzhou

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

Tangdu Hospital of The fourth Military Medical University Peoples Liberation Army of China, Xi'an

Xiamen Humanity Hospital, Xiamen

Henan Cancer Hospital, Zhengzhou

Henan Provincial People's Hospital, Zhengzhou

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

CStone Pharmaceuticals

INDUSTRY

NCT05297890 - A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter