Phase 1 First-in-human Study of JS014

PHASE1UnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 28, 2022

Primary Completion Date

June 30, 2024

Study Completion Date

January 31, 2025

Conditions
Neoplasm MalignantNeoplasm, ExperimentalSolid Tumor, AdultLymphoma
Interventions
BIOLOGICAL

JS014, Interleukin 21 and humanized anti-human serum albumin VHH antibody

Weekly infusion at the designated dose level until disease progression, withdrawal or up to two years

BIOLOGICAL

Pembrolizumab - anti-PD-1 antibody

200 mg, once every three weeks until disease progression, withdrawal or up to two years

Trial Locations (2)

106

RECRUITING

Wanfang Hospital -Taipei Medical University, Taipei

Unknown

RECRUITING

Taipei Medical University -Shuang Ho Hospital, New Taipei City

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Shanghai Junshi Bioscience Co., Ltd.

OTHER

lead

Anwita Biosciences

INDUSTRY

NCT05296772 - Phase 1 First-in-human Study of JS014 | Biotech Hunter | Biotech Hunter