Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

1,746

Participants

Timeline

Start Date

September 30, 2024

Primary Completion Date

September 30, 2028

Study Completion Date

March 31, 2029

Conditions
Acute Ischemic StrokeAtrial Fibrillation
Interventions
OTHER

Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version)

Therapy for early rhythm control will be either by use of approved antiarrhythmic drugs (e.g. amiodarone, dronedarone, flecainide, propafenone), approved approaches and devices for ablation, or electric cardio version.

OTHER

Usual care for atrial fibrillation

Usual care for atrial fibrillation according to current guidelines. Usual care will mainly comprise rate control by approved drugs. We expect, that usual care will also comprise therapy for rhythm control in a small group of patients.

All Listed Sponsors
collaborator

University Heart & Vascular Center Hamburg, Department of Cardiology

UNKNOWN

collaborator

Department of Neurology, Royal Melbourne Hospital

UNKNOWN

collaborator

Melbourne Heart Centre, Royal Melbourne Hospital

UNKNOWN

collaborator

Hotchkiss Brain Institute, University of Calgary

OTHER

collaborator

Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht

UNKNOWN

collaborator

UMC Utrecht

OTHER

collaborator

Edinburgh Clinical Trials Unit, Cerebrovascular Research Group, Centre for Clinical Brain Sciences, University of Edinburgh

UNKNOWN

collaborator

Department of Cardiovascular Sciences, University of Leicester British Heart Foundation Cardiovascular Research Centre

UNKNOWN

collaborator

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf

UNKNOWN

collaborator

CTC-NORTH

UNKNOWN

collaborator

Stroke Alliance for Europe (SAFE)

UNKNOWN

collaborator

Kompetenznetz Vorhofflimmern e.V. (AFNET)

UNKNOWN

lead

Universitätsklinikum Hamburg-Eppendorf

OTHER

NCT05293080 - Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE | Biotech Hunter | Biotech Hunter