314
Participants
Start Date
February 15, 2022
Primary Completion Date
January 2, 2023
Study Completion Date
March 30, 2024
PBSCs
PBSCs harvest is performed from day 5 of G-CSF to obtain at least 7.0×10\^8 total nucleated cells/kg recipient ideal body weight.
Cord
The criteria for cord selection included the following: (1) ≥3 of 6 HLA loci , (2) blood type matches, (3) contained a minimum cell count of 0.3×10\^8 nucleated cells/kg and 0.15×10\^6 CD34-positive cells/kg before freezing. The third party UCB will be infused the day after infusion of PBSCs.
BMSCs
BMSCs of donor will be collected and infused at least 0.5×10\^8 total nucleated cells/kg recipient ideal body weight the day after PBSCs infusion.
Department of Hematology,Nanfang Hospital, Southern Medical University, Guangzhou
First Affiliated Hospital of Guangxi Medical University
OTHER
Hunan Provincial People's Hospital
OTHER
The Seventh Affiliated Hospital of Sun Yat-sen University
OTHER
First People's Hospital of Chenzhou
OTHER
Dongguan People's Hospital
OTHER_GOV
The First People's Hospital of Guangzhou
UNKNOWN
Nanfang Hospital, Southern Medical University
OTHER