Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

March 28, 2022

Primary Completion Date

December 1, 2026

Study Completion Date

January 1, 2027

Conditions
RadiotherapyPD-1 InhibitorCapecitabineNasopharyngeal Carcinoma
Interventions
RADIATION

SBRT radiotherapy + Conventionally fractionated radiotherapy

Radiotherapy was performed 3-6 weeks after the end of first-line treatment, followed by conventional fractionated radiotherapy of the primary tumor and cervical lymph node metastases, SBRT radiotherapy of distant organ metastases 3-6 weeks later.

DRUG

PD-1 inhibitor

Immunotherapy of PD-1 inhibitor is used during the whole time of this trial until subjects were withdrawn from the trial or the trial complete

DRUG

Capecitabine

Capecitabine is treated for patients 3-6 weeks after radiotherapy, which combines with PD-1 inhibitor as the maintenance regimen in the trial.

Trial Locations (1)

Unknown

RECRUITING

Fifth Affilliated Hospital of Sun Yat-sen University, Zhuhai

All Listed Sponsors
lead

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER