Effect of Intrathecal Neostigmine on Post-dural Puncture Headache.

PHASE4CompletedINTERVENTIONAL
Enrollment

722

Participants

Timeline

Start Date

April 25, 2022

Primary Completion Date

July 25, 2023

Study Completion Date

July 25, 2023

Conditions
Post-Dural Puncture Headache
Interventions
DRUG

Neostigmine Methylsulfate

0.5 mg ampule (1 ml) will be diluted in 4 ml dextrose 5% to make a solution of 100 μg/ml, 0.2 ml of this solution will be added to 2.5 ml of hyperbaric bupivacaine 0.5 % used for intrathecal injection.

DRUG

Dextrose 5%/Nacl 0.9% Inj

one ml of normal saline 0.9 % will be mixed with 4 ml dextrose 5 % in the five-milliliter syringe. 0.2 ml of this mixture will be prepared at a one-milliliter identical syringe.

Trial Locations (1)

Unknown

Alexandria University, Alexandria

All Listed Sponsors
collaborator

Kasr El Aini Hospital

OTHER

collaborator

Fayoum University

OTHER

lead

Alexandria University

OTHER