Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301

PHASE3CompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

July 25, 2023

Primary Completion Date

January 24, 2024

Study Completion Date

January 24, 2024

Conditions
ADHDAttention Deficit Hyperactivity DisorderADHD - Combined TypeAttention Deficit Hyperactivity Disorder CombinedAttention-deficit HyperactivityAttention Deficit Hyper Activity
Interventions
DRUG

CTx-1301-Dexmethylphenidate 12.5 mg (titration only)

Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg

DRUG

CTx-1301-Dexmethylphenidate 18.75mg (randomized fixed dose)

Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg

DRUG

CTx-1301-Dexmethylphenidate 25mg (randomized fixed dose)

Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg, then week 2 to 25 mg

DRUG

CTx-1301-Dexmethylphenidate 37.5 mg (randomized fixed dose)

Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg, then week 2 to 25 mg, then week 3 to 37.5 mg

DRUG

Placebo

Subjects will be randomized at Visit 2 to Placebo

Trial Locations (24)

10029

Icahn School of Medicine at Mount Sinai, New York

23805

Clinical Research Partners LLC, Petersburg

29405

Coastal Carolina Research Center, North Charleston

29414

Coastal Pediatric Associates, Charleston

30331

Atlanta Center for Medical Research, Atlanta

32256

Clinical Neuroscience Solutions, Inc., Jacksonville

32751

Meridien Research, Maitland

32801

Clinical Neuroscience Solutions, Inc., Orlando

37203

Access Clinical Trials Inc., Nashville

38119

Clinical Neuroscience Solutions, Inc., Memphis

45409

Dayton Clinical Research, Dayton

48302

Neurobehavioral Medicine Group, Bloomfield Hills

63304

St Charles Psychiatric Associates & Midwest Research Group, Saint Charles

73112

SP Research PLLC, Oklahoma City

75231

FutureSearch Trials, Dallas

77090

Red Oak Psychiatry Associates, PA, Houston

77381

Family Psychiatry of The Woodlands, Woodland

77401

Houston Clinical Trials, Bellaire

77702

Gadolin Research, Beaumont

78759

BioBehavioral Research of Austin, Austin

89128

Center for Psychiatry and Behavioral Medicine. Inc., Las Vegas

97210

Summit Research Network, LLC, Portland

01103

Sisu Bhr, Llc, Springfield

08009

Hassman Research Institute, Berlin

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Premier Research

OTHER

lead

Cingulate Therapeutics

INDUSTRY

NCT05286762 - Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301 | Biotech Hunter | Biotech Hunter