Algorithm Using a Rapid Diagnostic Test for the Management of Childhood Febrile Diseases.

NACompletedINTERVENTIONAL
Enrollment

1,176

Participants

Timeline

Start Date

February 28, 2022

Primary Completion Date

February 28, 2022

Study Completion Date

November 30, 2023

Conditions
Antimicrobial Resistance
Interventions
DIAGNOSTIC_TEST

Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)

"The interpretation of the two-step malaria RDT will be done as follow:~* PfHRP2(+)/pLDH(+): falciparum malaria or co-infection with non-falciparum malaria;~* PfHRP2(-)/pLDH(+): non-falciparum malaria or falciparum malaria with deletion of hrp2;~* PfHRP2(-)/pLDH(-): negative results~* PfHRP2(+)/pLDH(-): inconclusive results and information on previous antimalarial treatment is needed to differentiate:~Within the past 28 days:~* If previous antimalarial treatment is reported, the malaria diagnosis is reported as negative result. Nonetheless, the antimalarial treatment decision will be based on malaria microscopy;~* If previous antimalarial treatment is not reported, the malaria diagnosis is reported as positive result.~Other PoC tests for bacterial infections The two-step malaria RDT will be supported by PoC test listed above to diagnose bacterial or viral infection in all patients."

Trial Locations (2)

11 BP 218 Ouaga CMS 11

Institut de Recherche en Sciences de la Santé-Clinical Research Unit of Nanoro, Nanoro

Unknown

Health District of Nanoro, Nanoro

All Listed Sponsors
lead

Institut de Recherche en Sciences de la Sante, Burkina Faso

OTHER_GOV