135
Participants
Start Date
April 10, 2022
Primary Completion Date
March 20, 2023
Study Completion Date
March 30, 2023
Dexmedetomidine infusion
Patients received dexmedetomidine (0.5 µg/kg over 10 min before the induction of anesthesia), and then dexmedetomidine was infused at a rate of 0.4 μg/kg/h until 20 min before the end of operation
Co-administration dexmedetomidine and low-dose esketamine infusion
Patients received a bolus infusion of dexmedetomidine (0.5 µg/kg) and esketamine (0.5 mg/kg)over 10 min before the induction of anesthesia, and then dexmedetomidine were infused at a rate of 0.4 µg/kg/h and 2 µg/kg/min until 20 min before the end of operation, respectively.
Co-administration dexmedetomidine and high-dose esketamine infusion
Patients received a bolus infusion of dexmedetomidine (0.5 µg/kg) and esketamine (0.5 mg/kg)over 10 min before the induction of anesthesia, and then dexmedetomidine were infused at a rate of 0.4 µg/kg/h and 4 µg/kg/min until 20 min before the end of operation, respectively.
Department of Anqing Hospital Anesthesiology, Anqing
Anqing Municipal Hospital
OTHER