Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

September 30, 2022

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
CarcinomaRecurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
Interventions
DRUG

NRC-2694-A

300 mg orally once daily

DRUG

Paclitaxel

175 mg/m² IV infusion over approximately 3 hours

Trial Locations (12)

18045

Salib Oncology, Easton

33176

Miami Cancer Center, Miami

33486

Lynn Cancer Center, Boca Raton

40001

Daycare Angels under AOH, Mumbai

40202

Norton Cancer Institute - Downtown, Louisville

53792

University of Wisconsin Carbone Cancer Center, Madison

63110

Washington University - Siteman Cancer Center, St Louis

90017

Los Angeles Hematology Oncology Medical Group, Los Angeles

92835

Providence Medical Foundation -Fullerton, Fullerton

411001

Grant Medical Foundation Ruby Hall Clinic, Pune

21201-1544

University of Maryland Greenebaum Cancer Center, Baltimore

03756-1000

Dartmouth Hitchcock Medical Center, Lebanon

Sponsors

Lead Sponsor

All Listed Sponsors
lead

NATCO Pharma Ltd.

INDUSTRY