HPV 16-positive and/or HPV 18-positive Recurrent and/or For Patients With Metastatic Head and Neck Cancer to Evaluate GX-188E DNA Vaccination, GX-I7 and Nivolumab Combination Therapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

April 15, 2022

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG

nivolumab-GX-188E-GX-I7

"* Nivolumab 3 mg/kg IV administered every 2 weeks~* GX-188E 2 mg IM at Weeks 1, 2, 4, 7, 10, 13, and 19~* GX-I7 1200 μg/kg or the recommended dose of the introductory safety cohort is administered at weeks 2, 10, and 18"

Trial Locations (1)

Unknown

RECRUITING

Yonsei University Health System, Severance Hospital, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER