Ovarian PRP (Platelet Rich Plasma) Injection for Follicular Activation

NAActive, not recruitingINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

March 17, 2022

Primary Completion Date

April 30, 2025

Study Completion Date

June 30, 2030

Conditions
Premature Ovarian InsufficiencyInfertility, FemaleSterility, FemalePRP
Interventions
BIOLOGICAL

autologous PRP (platelet rich plasma)

The required volume of PRP will be extracted from 60 ml of the patient's peripheral blood. Injecting PRP into the ovaries will be performed likewise to the standard operating procedure of oocyte retrieval. After centrifugation of the whole blood, 5ml PRP will be injected in each ovary intra-medullar and subcortical using a 17-gauge single lumen needle under sedation und under transvaginal ultrasound monitoring.

OTHER

Saline solution (NaCL) Injection

Injecting NaCL into the ovaries will be performed likewise to the standard operating procedure of oocyte retrieval. NaCL will be injected in each ovary intra-medullar and subcortical using a 17-gauge single lumen needle under sedation und under transvaginal ultrasound monitoring.

Trial Locations (1)

23562

University of Luebeck, Lübeck

All Listed Sponsors
lead

University of Luebeck

OTHER