Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis

NACompletedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

May 11, 2022

Primary Completion Date

September 30, 2022

Study Completion Date

September 30, 2022

Conditions
De Novo Lipogenesis (DNL)
Interventions
OTHER

Assessment of de novo lipogenesis non-invasively in exhaled breath

"1. Healthy participants have a good nights sleep whereas they don't eat during the night and until measurements.~2. They come to the lab and make first baseline exhalation sets. An exhalation set consists of 6 exhalations in Mass Spectrometer positive mode and the same in negative mode. One exhalation set takes around 7minutes from start to finish.~3. Participants consume a single oral dose of dose of 70% 2H2O at 2 g/kg body-water.~4. Participants execute several exhalation sets over time.~5. Participants consume 300g of 'Excellence Joghurt Nature gezuckert.~6. Participants execute several exhalation sets over time.~7. After around 4.5hours with regular exhalation sets taking place, the trial is concluded."

Trial Locations (1)

4056

University Children's Hospital Basel (UKBB), Basel

All Listed Sponsors
collaborator

Swiss National Science Foundation

OTHER

collaborator

Fondation Botnar

UNKNOWN

lead

University Children's Hospital Basel

OTHER