Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy

CompletedOBSERVATIONAL
Enrollment

93

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

August 20, 2024

Study Completion Date

September 17, 2024

Conditions
Acute Kidney InjuryChronic Kidney Disease Stage 5 on DialysisChronic Kidney FailureIntradialytic HypotensionFluid Overload
Interventions
DIAGNOSTIC_TEST

Estimated absolute blood volume

Baseline absolute blood volume will be inferred based on the change in relative blood volume (RBV) after a single 240mL replacement fluid infusion and then monitored throughout the session via the RBV value.

DIAGNOSTIC_TEST

Modified VExUS evaluation

The presence of at least 2/3 abnormal venous Doppler waveforms at the following sites: Portal vein, hepatic vein, and femoral vein.

Trial Locations (1)

H2X 0C1

Centre Hospitalier de l'Université de Montréal, Montreal

All Listed Sponsors
collaborator

The Kidney Foundation of Canada

OTHER

lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER