Neoadjuvant Chemotherapy for Pancreatic Cancer Followed by GS and GnP

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2030

Conditions
Pancreatic Adenocarcinoma
Interventions
DRUG

GS

drip infusion of gemcitabine plus oral administration of S-1 S-1 received S-1 orally twice daily at a dose calculated according to body-surface area (BSA) (\< 1.25 m2, 60 mg/d; ≥ 1.25 to \< 1.5 m2, 80 mg/d; ≥ 1.5 m2, 100 mg/d) on days 1 through 14 of a 21-day cycle gemcitabine received gemcitabine intravenously at a dose of 800 mg/m2 over 30 minutes on days 1 and 8of a 21-day cycle.

DRUG

GnP

"drip infusion of both gemcitabine and nab-paclitacel gemcitabine received gemcitabine intravenously at a dose of 800 mg/m2 over 30 minutes on days 1, 8, and 15 of a 28-day cycle.~nab-paclitaxel received nab-paclitaxel intravenously at a dose of 100 mg/m2 over 30 minutes on days 1, 8, and 15 of a 28-day cycle."

Trial Locations (1)

781-8555

RECRUITING

Takehiro Okabayashi, Kochi

All Listed Sponsors
lead

Kochi University

OTHER