Ethnic Differences in Mechanisms of Action of Dupilumab

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 25, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Atopic Dermatitis
Interventions
DRUG

Dupilumab

"Patients will be treated with dupilumab for 4 months (standard FDA-approved dosing of 600 mg subcutaneously at baseline/week 0, followed by 300 mg every 2 weeks).~Skin biopsies will be assessed at baseline (lesional and non-lesional), week 2 (lesional), and week 16 (lesional). In addition, blood will be obtained at baseline and week 16."

Trial Locations (1)

48109

RECRUITING

University of Michigan, Ann Arbor

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

University of Michigan

OTHER