Valacyclovir in Pain Management of Acute Apical Abscesses

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 25, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Acute Apical AbscessPain, Acute
Interventions
DRUG

Valacyclovir 500 MG

Consistent with the pilot study VEII will use a random number generator to randomly assign a Manila packet containing amoxicillin 500mg + Valtrex (valacyclovir 500mg x three times daily for 7 days). Opaque medication packaging and using standardized verbal and written instructions helps ensure blindness of the VEII calibrated clinician, and patients of the therapeutic group they were assigned to.

DRUG

Placebo

Consistent with the pilot study VEII will use a random number generator to randomly assign a Manila packet containing amoxicillin 500mg + Placebo (empty capsule). Opaque medication packaging and using standardized verbal and written instructions helps ensure blindness of the VEII calibrated clinician, and patients of the therapeutic group they were assigned to.

Trial Locations (1)

94143

RECRUITING

UCSF Dental, San Francisco

All Listed Sponsors
lead

University of California, San Francisco

OTHER