Study of BO-112 With Radiotherapy and Nivolumab for Metastatic Refractory NSCLC

PHASE1/PHASE2UnknownINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 13, 2022

Primary Completion Date

March 31, 2024

Study Completion Date

June 30, 2024

Conditions
Non-Small Cell Lung Cancer Metastatic
Interventions
DRUG

BO-112 in combination with ablative radiotherapy (SABR) and nivolumab

Study treatment will consist of BO-112 IT injections in combination with IV nivolumab infusions and SABR to accessible metastases.

PROCEDURE

Tissue Biopsies

Four research biopsies will be taken from accessible injected lesions, at the time of the IT injection of BO-112.

Trial Locations (1)

31008

RECRUITING

Clínica Universidad de Navarra, Pamplona

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Highlight Therapeutics

INDUSTRY

lead

Clinica Universidad de Navarra, Universidad de Navarra

OTHER