Retrospective Analysis of the Effects of Perioperative Osteoanabolic Treatment on Patients With Spinal (Fusion) Surgery.

CompletedOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

July 20, 2021

Primary Completion Date

November 1, 2021

Study Completion Date

November 1, 2022

Conditions
Spinal (Fusion) Surgery
Interventions
OTHER

Data collection (Laboratory tests, Radiologic diagnostics, Patient data taken from existing medical charts)

Data collection: Bone turnover laboratory parameters: alkaline phosphatase (AP), calcium (corrected for albumin), PTH, Calcidiol (25-OH-D3), N-terminales Kollagen Typ 1 -. Propeptid (P1NP), glomerular filtration rate (GFR), calcium/creatinine (in urine); Radiologic diagnostics: Bone densitometry (DEXA), X-rays, computer tomograms, MRI for analysis of time of the bone healing (or a non-union); Patient data taken from existing medical charts: side effects, tolerability of PTH, patient compliance, presence of previous illnesses as risk factors for the formation of pseudoarthrosis, indication for therapy, time at which therapy started and length of therapy with PTH, precise characterization of the operation (type and whether it is a revision or first operation).

Trial Locations (1)

4031

Department of Orthopaedics and Traumatology, University Hospital Basel, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER

NCT05264610 - Retrospective Analysis of the Effects of Perioperative Osteoanabolic Treatment on Patients With Spinal (Fusion) Surgery. | Biotech Hunter | Biotech Hunter