A Study of CM350 in Patients With Advanced Solid Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

April 21, 2022

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2027

Conditions
Advanced Solid Tumor
Interventions
BIOLOGICAL

CM350 group1

CM350 will be administered intravenously (IV) once a week (QW) through step-up dosing until the participant discontinues study treatment, develops disease progression, initiates a new anti-tumor therapy, develops unacceptable toxicity, death, lost to follow-up, the investigator discontinue study treatment, or a female participant becomes pregnant (whichever occurs first).

BIOLOGICAL

CM350 group2

CM350 will be administered intravenously (IV) once a week (QW) through step-up dosing until the participant discontinues study treatment, develops disease progression, initiates a new anti-tumor therapy, develops unacceptable toxicity, death, lost to follow-up, the investigator discontinue study treatment, or a female participant becomes pregnant (whichever occurs first).

BIOLOGICAL

CM350 group3

CM350 will be administered intravenously (IV) once a week (QW). Individual subjects may continue study treatment until the participant discontinues study treatment, develops disease progression, initiates a new anti-tumor therapy, develops unacceptable toxicity, death, lost to follow-up, the investigator discontinue study treatment, or a female participant becomes pregnant (whichever occurs first).

Trial Locations (2)

Unknown

RECRUITING

West China Hospital of Sichuan University, Chengdu

RECRUITING

Zhongshan Hospital Affiliated to Fudan University, Shanghai

Sponsors
All Listed Sponsors
lead

Keymed Biosciences Co.Ltd

INDUSTRY

NCT05263960 - A Study of CM350 in Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter