Study Assessing Pain Relief After Replacement of the Knee

PHASE2TerminatedINTERVENTIONAL
Enrollment

112

Participants

Timeline

Start Date

June 7, 2022

Primary Completion Date

January 15, 2024

Study Completion Date

January 15, 2024

Conditions
Acute Postoperative Pain
Interventions
DRUG

ATX-101

ATX-101 (bupivacaine) implant, one-time administration into the surgical site

DRUG

ATX-101

ATX-101 (bupivacaine) implant, one-time administration into the surgical site

DRUG

bupivacaine hydrochloride without epinephrine

bupivacaine hydrochloride (125 mg) without epinephrine via local infiltration and/or nerve block

Trial Locations (13)

2031

Prince of Wales Private Hospital, Sydney

3181

The Avenue Private Hospital, Windsor

4224

John Flynn Private Hospital, Tugun

5000

Royal Adelaide Hospital / PARC Clinical Research, Adelaide

St Andrew's Private Hospital, Adelaide

L1S 7K7

Durham Bone and Joint Specialists, Ajax

C9 124

London Health Sciences Centre - University Hospital, London

CB2 0QQ

Department of Trauma and Orthopaedic Surgery, Addenbrooke's Hospital, Cambridge

SO16 6YD

Southampton General Hospital, Southampton

HA7 4LP

Royal National Orthopaedic Hospital, Stanmore

NG5 1PB

Nottingham Elective Orthopaedic Service, Nottingham University Hospitals, Nottingham

SY10 7AG

Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry

LS7 4SA

Chapel Allerton Hospital C/O The Leeds Teaching Hospitals NHS Trust, Leeds

Sponsors
All Listed Sponsors
lead

Allay Therapeutics, Inc.

INDUSTRY