Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen for Elderly Patients With Acute Myeloid Leukemia: A Phase II Single-Arm Multicenter Study

NARecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

January 21, 2022

Primary Completion Date

January 21, 2024

Study Completion Date

January 21, 2026

Conditions
Acute Myeloid Leukemia
Interventions
DRUG

rhTPO

decitabine (15 mg/m2 daily, days 1-5); low-dose cytarabine (10 mg/m2 q12 h, days 3-9); rhTPO (15,000 U daily, days 2, 4, 6, 8, and 10-24 or until a platelet count \> 50 × 109/L was observed); aclarubicin (14 mg/m2 daily, days 3-6); and G-CSF (300 μg daily, days 2-9).

Trial Locations (1)

110004

RECRUITING

ShengJing Hospital of China Medical University, Shenyang

All Listed Sponsors
lead

Huihan Wang

OTHER