An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

September 4, 2025

Study Completion Date

September 4, 2025

Conditions
Gastric and Gastroesophageal Junction Carcinoma
Interventions
DRUG

Atezolizumab

Atezolizumab is administered by IV infusion on Day 1 of each 21 day cycle. Treatment until progressive disease.

DRUG

Capecitabine

Capecitabine is administered orally twice daily on Days 1-14 of each 21 day cycle. Treatment for up to six cycles.

DRUG

Oxaliplatin

Oxaliplatin is administered by IV infusion on Day 1 of each 21 day cycle. Treatment for up to six cycles.

DRUG

Tiragolumab

Tiragolumab is administered by IV infusion on Day 1 of each 21 day cycle.

Trial Locations (12)

100080

The General Hospital of People?s Liberation Army (301 Hospital), Beijing

130021

the First Hospital of Jilin University, Changchun

210008

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing

226361

Nan Tong Tumor Hospital, Nantong

230601

The Second Affiliated Hospital of Anhui Medical University, Hefei

272000

Affiliated Hopsital of Jining Medical University, Jining

310003

The First Affiliated Hospital, Zhejiang University, Hangzhou

310016

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou

341000

First Affiliated Hospital of Gannan Medical University, Ganzhou

450052

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

710061

The First Affiliated Hospital of Xian Jiao Tong University, Xi'an

030013

Shanxi Province Cancer Hospital, Taiyuan

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY