21
Participants
Start Date
June 16, 2022
Primary Completion Date
January 21, 2025
Study Completion Date
January 21, 2025
Eosinophilic Esophagitis (EoE) food introduction-1st
1 serving size of food proven to induce histologic and clinical symptoms in EoE
Eosinophilic Esophagitis (E0E) food introduction-2nd
Either 1 serving size of different food (not food in arm 1) to induce histologic and clinical symptoms in EoE or Increase the food in arm 1 to 2 serving size a day
Eosinophilic Esophagitis (EoE) Food introduction-3rd dose
Either 1 serving size of different food (not food in arm 1 or 2) to induce histologic and clinical symptoms in EoE or Increase the food in arm 2 to 2 serving size a day or unlimited amounts of food arm 1
Dupilumab
"All patients will receive open label dupilumab at the following doses \>12 years of age \> 40 kg 300 subcutaneous (SQ) weekly~6-11 years of age 5-15 kg 100 mg SQ every 2 weeks (Q2W) 15-30 kg 200 mg SQ Q2W \>30-60 kg 300 mg SQ Q2W"
Children's Hospital of Philadelphia, Philadelphia
Regeneron Pharmaceuticals
INDUSTRY
Genzyme, a Sanofi Company
INDUSTRY
Children's Hospital of Philadelphia
OTHER