Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

Not yet recruitingOBSERVATIONAL
Enrollment

2,000

Participants

Timeline

Start Date

July 31, 2022

Primary Completion Date

February 29, 2032

Study Completion Date

February 29, 2032

Conditions
PolypharmacyPharmacogeneticsPharmacogenomic TestingDrug-Related Side Effects and Adverse Reactions
Interventions
GENETIC

Pharmacogenomic testing of a panel of important pharmacogenes to detect genetic variants and evaluate the association between genetically predicted and measured drug metabolism

All planned interventions are explorative analyses of biological and genetic risk profiles that can contribute to patients' individual risk for adverse drug reactions, i.e. due to variability in drug metabolism

OTHER

Adverse Drug Reaction detection

During appointments in the university outpatient clinic, patients will undergo a comprehensive adverse drug reaction (ADR) assessment based on an ADR diary they were handed at enrolment

OTHER

Falls Efficacy Scale International (FES-I)

The FES-I wil be obtained to estimate fear of falling

All Listed Sponsors
collaborator

B. Braun Foundation

OTHER

lead

RWTH Aachen University

OTHER

NCT05247814 - Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients | Biotech Hunter | Biotech Hunter