ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

April 30, 2022

Primary Completion Date

March 31, 2023

Study Completion Date

December 31, 2033

Conditions
Esophageal CancerEsophagogastric Junction Cancer
Interventions
DRUG

Intravenous Tislelizumab

Participants will receive 200mg, every three weeks for up to 51 weeks

DRUG

Chemotherapy

Carboplatin (AUC2) and Paclitaxel (50mg/m2), Weekly x 5 weeks

RADIATION

Fractionated radiation

Concurrent with chemo, x5 weeks

PROCEDURE

Esophagectomy

Surgical resection of cancer after chemoradiation therapy when no disease progression found.

Trial Locations (1)

40536

University of Kentucky, Lexington

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BeiGene

INDUSTRY

collaborator

University of Kentucky

OTHER

lead

Zhonglin Hao

OTHER