A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

June 30, 2022

Primary Completion Date

April 30, 2025

Study Completion Date

April 30, 2025

Conditions
Solid Tumor
Interventions
DRUG

ABSK061

In the escalation part, patients will receive a single dose of oral ABSK061 on C1D1 only, and then BID dosing for the rest of the days of cycle 1 and in subsequent cycles (28-day cycles). The starting dose is 5 mg BID. In the expansion part, patients will each receive oral ABSK061 at the RDE in repeated 28-day cycles.

Trial Locations (22)

75230

RECRUITING

Mary Crowley Cancer Research, Dallas

201203

RECRUITING

Yuan LU, Shanghai

Unknown

RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

NOT_YET_RECRUITING

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

NOT_YET_RECRUITING

Chongqing Daping Hospital, Chongqing

NOT_YET_RECRUITING

Fujian Cancer Hospital, Fuzhou

RECRUITING

Zhejiang Cancer Hospital, Hangzhou

RECRUITING

Sun Yat-sen Memorial Hospital/ the Second Affiliated Hospital of Sun Yat-sen University, Guanzhou

NOT_YET_RECRUITING

Harbin Medical University Cancer Hospital, Harbin

RECRUITING

Henan Cancer Hospital, Zhengzhou

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

NOT_YET_RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

NOT_YET_RECRUITING

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot

RECRUITING

Xuzhou Center Hospital, Xuzhou

RECRUITING

First Hospital of Jilin University, Changchun

NOT_YET_RECRUITING

JILIN Cancer Hospital, Changchun

NOT_YET_RECRUITING

Yunnan Cancer Hospital, Yunnan

RECRUITING

Liaoning Province Cancer Hospital, Shenyang

NOT_YET_RECRUITING

The First Hospital of China Medical University, Shenyang

NOT_YET_RECRUITING

Shanghai Chest Hospital, Shanghai

RECRUITING

Chongqing University Cancer Hospital, Chongqing

RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hanzhou

Sponsors
All Listed Sponsors
lead

Abbisko Therapeutics Co, Ltd

INDUSTRY

NCT05244551 - A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter