A Study to Evaluate the Safety and Pharmacokinetics of XMAB24306 in Combination With Daratumumab in Participants With Relapsed/Refractory Multiple Myeloma

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

April 28, 2022

Primary Completion Date

July 10, 2024

Study Completion Date

July 10, 2024

Conditions
Multiple Myeloma
Interventions
DRUG

XmAb24306

XmAb24306 will be given via intravenous (IV) infusion

DRUG

Daratumumab

Participants will receive daratumumab via subcutaneous (SC) injection every week for Cycles 1-4, every 2 weeks for Cycles 5-12, and every 4 weeks thereafter (cycle length = 2 weeks for Cycles 1-12 and 4 weeks thereafter)

Trial Locations (7)

3004

Alfred Hospital, Melbourne

5000

Royal Adelaide Hospital, Adelaide

Odense Universitetshospital, Odense C

7100

Sygehus Lillebælt, Vejle, Vejle

0450

Oslo Universitetssykehus HF, Oslo

08916

Hospital Universitario Germans Trias i Pujol, Badalona

08035

Hospital Universitari Vall d'Hebron, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY