Imaging Sodium and Lymphatics in Lymphedema

Active, not recruitingOBSERVATIONAL
Enrollment

75

Participants

Timeline

Start Date

October 10, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Lymphedema of LegLymphedema, SecondaryLymphedema Related Fibrosis
Interventions
PROCEDURE

Complete decongestive therapy

The investigators will identify participants undergoing clinically-indicated interventions that they are already receiving for their routine clinical management (complete decongestive physical therapy). They will make no evaluation of the efficacy of these procedures, but rather will test fundamental hypotheses regarding lymphatic clearance of tissue sodium.

OTHER

Standard imaging protocol

The standard imaging protocol entails noninvasive magnetic resonance imaging techniques including sodium and lymphatic angiography.

Trial Locations (1)

22903

University of Virginia, Charlottesville

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Vanderbilt University Medical Center

OTHER

lead

University of Virginia

OTHER