A Study to Investigate the Safety and Efficacy of GB1211 (a Galectin-3 Inhibitor) in Combination With Atezolizumab in Patients With Non-Small Cell Lung Cancer (NSCLC).

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

March 15, 2022

Primary Completion Date

May 30, 2024

Study Completion Date

November 1, 2025

Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG

GB1211

GB1211 is a galectin 3 inhibitor an orally available small molecular anti-fibrotic. It is administered orally twice a day.

DRUG

Placebo

Placebo is administered orally twice a day.

DRUG

Atezolizumab

Atezolizumab is an PD-L1 inhibitor administered as an intravenous infusion every three weeks at a dose of 1200mg

Trial Locations (5)

21000

Centre Georges Grancois Leclerc, Dijon

37044

CHRU, Tours

46026

Hospital Universitario y Politécnico La Fe, Valencia

10-357

Samodzielny Publiczny Zespol Gruzlicy I Chorob Pluc, Olsztyn

08035

Hospital Universitari Vall d'Hebron, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Linical Europe GmbH

UNKNOWN

collaborator

Hoffmann-La Roche

INDUSTRY

lead

Galecto Biotech AB

INDUSTRY