Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

January 21, 2022

Primary Completion Date

September 30, 2025

Study Completion Date

March 31, 2040

Conditions
Rejection; Transplant, LiverLiver FailureLiver Diseases
Interventions
DRUG

QEL-001

QEL-001 is an autologous therapy that is composed of engineered regulatory T cells transduced with a lentiviral vector containing a CAR directed against HLA-A2. Treatment will be given via an IV infusion.

Trial Locations (10)

3000

RECRUITING

UZ Leuven, Leuven

Unknown

RECRUITING

H. Saint Luc, Brussels

RECRUITING

Hopital Erasme, Brussels

RECRUITING

H. Clinic Barcelona, Barcelona

RECRUITING

Hospital Reina Sofia, Córdoba

RECRUITING

G. Gergorio Maranon, Madrid

RECRUITING

Queen Elizabeth Hospital, Birmingham

CB2 0QQ

RECRUITING

Cambridge University Hospitals NHS Foundation Trust, Cambridge

NW3 2QG

RECRUITING

Royal Free London NHS Foundation Trust, London

SE5 9RS

RECRUITING

King's College Hospital NHS Foundation Trust, London

All Listed Sponsors
lead

Quell Therapeutics Limited

INDUSTRY