140
Participants
Start Date
July 1, 2022
Primary Completion Date
June 30, 2027
Study Completion Date
June 30, 2027
Metformin hydrochloride (HCl) 500mg tablet
"Metformin HCl 500mg tablets contain 500mg of active pharmaceutical ingredient (API) and are white, round, biconvex, film-coated tablets, with a score line on one face and debossed with HMR on the other. Each tablet contains the non-medicinal ingredients magnesium stearate and povidone. Tablet coating is comprised of hydroxypropyl methylcellulose, polyethylene glycol and titanium dioxide."
Placebo
Matching white round tablet containing excipients only. The placebo tablets will match the active drug as closely as possible in terms of appearance.
WITHDRAWN
Children's Hospital in Westmead, Westmead
RECRUITING
John Hunter Children's Hospital, New Lambton Heights
RECRUITING
Royal Children's Hospital, Parkville
RECRUITING
Monash Children's Hospital, Clayton
RECRUITING
Perth Children's Hospital, Nedlands
RECRUITING
Alberta Children's Hospital, Calgary
RECRUITING
Stollery Children's Hospital, Edmonton
RECRUITING
Children's & Women's Health Centre of British Columbia, Vancouver
RECRUITING
Cancer Care Manitoba, Winnipeg
RECRUITING
Izaak Walton Killam (IWK) Health Centre, Halifax
RECRUITING
Hamilton Health Sciences - McMaster Children's Hospital, Hamilton
RECRUITING
Children's Hospital, London Health Sciences Centre, London
RECRUITING
Children's Hospital of Eastern Ontario, Ottawa
RECRUITING
The Hospital for Sick Children, Toronto
RECRUITING
CHU Sainte-Justine, Montreal
RECRUITING
Montreal Children's Hospital, Montreal
RECRUITING
CHU de Québec - Université Laval, Québec
RECRUITING
CHU de Sherbrooke, Sherbrooke
RECRUITING
Saskatchewan Health Authority, Saskatoon
Donald Mabbott
OTHER