Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

NARecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

October 5, 2022

Primary Completion Date

March 1, 2028

Study Completion Date

June 1, 2028

Conditions
Ulcerative ColitisCrohn Disease
Interventions
OTHER

Pragmatic

"Patients randomized to a strategy of switching TIM will be switched to one of the preferred agents recommended by clinical guidelines and covered by the patients' insurance formulary as part of routine care, and at the discretion of the site investigator and treating provider. No study-related medications will be provided.~Patients (and their providers) in either treatment arm will be allowed to stop or start new TIMs and other IBD-directed therapies in case of symptomatic relapse or intolerance to therapies, at the discretion of the treating provider-patient team."

Trial Locations (22)

10016

RECRUITING

NYU Langone Health, New York

10021

RECRUITING

Cornell University, New York

12027

RECRUITING

Saratoga Schenectady Gastroenterology Associates, Burnt Hills

14642

RECRUITING

University of Rochester, Rochester

20007

RECRUITING

MedStar Georgetown University Hospital, Washington D.C.

22908

WITHDRAWN

University of Virginia, Charlottesville

32224

RECRUITING

Mayo Clinic Jacksonville, Jacksonville

38138

WITHDRAWN

GastroOne, Germantown

60637

RECRUITING

University of Chicago Medicine, Chicago

73102

NOT_YET_RECRUITING

Hightower Clinical, Oklahoma City

75235

RECRUITING

University of Texas Southwestern, Dallas

77030

RECRUITING

Baylor College of Medicine, Houston

80045

RECRUITING

University of Colorado, Aurora

84132

RECRUITING

University of Utah Health, Salt Lake City

90048

RECRUITING

Cedars-Sinai, Los Angeles

92037

RECRUITING

UC San Diego Health, La Jolla

92618

RECRUITING

Hoag Hospital, Irvine

94301

RECRUITING

Sutter Health, Palo Alto

97220

WITHDRAWN

Oregon Clinic, Portland

06510

RECRUITING

Yale University, New Haven

03756

RECRUITING

Dartmouth Hitchcock, Lebanon

02904

RECRUITING

Gastroenterology Associates, Providence

All Listed Sponsors
collaborator

Baylor College of Medicine

OTHER

collaborator

Crohn's and Colitis Foundation

OTHER

collaborator

Western University

OTHER

collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

University of California, San Diego

OTHER