Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

April 22, 2022

Primary Completion Date

May 2, 2023

Study Completion Date

November 30, 2025

Conditions
Homozygous Familial Hypercholesterolemia
Interventions
DRUG

ARO-ANG 3 Injection

Participants will be randomized to receive ARO-ANG3 SC on Day 1 and Day 84 during the initial 36 Weeks of the study and on Day1 and Months 3, 6, 9, 12, 15, 18, and 21 of the extension period

Trial Locations (7)

2050

Research Site 8, Camperdown

2193

Research Site 7, Johannesburg

6009

Research Site 3, Nedlands

10029

Research Site 4, Mount Sinai

45227

Research Site 5, Cincinnati

G7H 7K9

Research Site 2, Chicoutimi

G1V 4W2

Research Site 1, Québec

Sponsors
All Listed Sponsors
lead

Arrowhead Pharmaceuticals

INDUSTRY