Autogenous vs. Xenogeneic Peri-implant Soft Tissue Grafts Placed in Full vs. Split Thickness Flaps

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 24, 2022

Primary Completion Date

December 15, 2023

Study Completion Date

December 1, 2024

Conditions
Thin Gingiva
Interventions
PROCEDURE

Split thickness flap

Palatally displaced crestal incision at the edentulous site, combined with the split thickness elevation of a buccal flap, extended to the sulcus of the adjacent mesial and distal tooth. Flap elevation performed with a micro-blade, in a buccal and apical direction, for approximately 15mm apical to the crestal incision.

PROCEDURE

Full thickness flap

Palatally displaced crestal incision at the edentulous site, combined with the full thickness elevation of a buccal flap, extended to the sulcus of the adjacent mesial and distal tooth. Flap elevation performed with a fine periosteal elevator, in a buccal and apical direction, for approximately 15mm apical to the crestal incision.

PROCEDURE

Autogenous sub epithelial connective tissue graft

Harvest of a sub epithelial connective tissue graft using a double incision technique, approximately 2-3 mm apical to the palatal gingival margins of the first and second premolars. Graft dimension standardised as 10mm (mesio-distally) by 6-8mm (apico-coronally) by 1,5mm (thickness). Graft stabilised at the inner aspect of the buccal flap, 1mm apical to the flap margin, using one mesial and one distal horizontal mattress sutures.

PROCEDURE

Volume stable collagen matrix

Geistlich Fibro-Gide® matrix shaped at a standardised dimension of 10mm (mesio-distally) by 6-8mm (apico-coronally) by 6mm (thickness). Matrix stabilised at the inner aspect of the buccal flap, 1mm apical to the flap margin, using one mesial and one distal horizontal mattress sutures.

Trial Locations (1)

28040

Department of Periodontology, University Complutense Madrid, Spain, Madrid

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Osteology Foundation

OTHER

lead

Universidad Complutense de Madrid

OTHER

NCT05211115 - Autogenous vs. Xenogeneic Peri-implant Soft Tissue Grafts Placed in Full vs. Split Thickness Flaps | Biotech Hunter | Biotech Hunter