NCT05210270 - HYpofractionated Pelvic Radiotherapy for Advanced Cervical Cancers INeligible for ChemoTherapy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2030

Conditions

Locally Advanced Cervical Carcinoma

Interventions

RADIATION

Hypofractionation

"Phase 1 (Dose Escalation Study):~Pelvic hypofractionated radiotherapy (40 Gy over 15 daily fractions) with nSIB 45 Gy (first dose level) and 48 Gy (second dose level); to be followed by brachytherapy (6.5-7.5 Gy x 4 fractions)~Phase 2 (Efficacy Study):~Pelvic hypofractionated radiotherapy (40 Gy over 15 daily fractions) with (or without) nSIB 45-48 Gy (depending on phase 1 results); to be followed by brachytherapy (6.5-7.5 Gy x 4 fractions)"

All Listed Sponsors

collaborator

Philippine Council for Health Research & Development

OTHER_GOV

lead

University of Santo Tomas Hospital, Philippines

OTHER