A Safety and Tolerability Study of Sotrovimab (VIR-7831) Prophylaxis Against COVID-19 in Immunocompromised Individuals

PHASE2CompletedINTERVENTIONAL
Enrollment

93

Participants

Timeline

Start Date

February 7, 2022

Primary Completion Date

February 28, 2023

Study Completion Date

February 28, 2023

Conditions
SARS CoV 2 Infection
Interventions
DRUG

Sotrovimab

Two intravenous (IV) doses of sotrovimab were administered over the study period, the first 500mg, and the second 2000mg, in light of the reduced antiviral neutralization of sotrovimab against the BA.2 subvariant.

Trial Locations (3)

02114

Massachusetts General Hospital, Boston

02115

Brigham and Women's Hospital, Boston

02215

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

GlaxoSmithKline

INDUSTRY

lead

Sophia Koo, M.D.

OTHER

NCT05210101 - A Safety and Tolerability Study of Sotrovimab (VIR-7831) Prophylaxis Against COVID-19 in Immunocompromised Individuals | Biotech Hunter | Biotech Hunter