Oral Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

July 1, 2027

Study Completion Date

October 1, 2027

Conditions
Pediatric Ulcerative Colitis in Remission
Interventions
DRUG

Fecal Microbiota Transplantation by Stool capsules

"After colon cleansing using PolyEthylen glycol, the patient will have a colonoscopy under general anaesthesia.~The patient will then receive orally FMT (frozen stools capsules prepared from healthy donor feces)."

DRUG

Fecal Microbiota Transplantation by Intra-rectal enemas

"After colon cleansing using Polyethylen glycol, the patient will have a colonoscopy under general anaesthesia.~The patient will then receive first FMT (frozen preparation of stools) by infusion in caecum during colonoscopy and the second and third doses by enemas."

Trial Locations (3)

75012

Department of gastroenterology, Armand Trousseau Hospital, Paris

75015

Department of Pediatric Gastroenterology, Hepatology and Nutrition - Necker - Enfants Malades Hospital, Paris

75019

Department of Pediatric Gastroenterology, Robert Debré Hospital, Paris

All Listed Sponsors
collaborator

MRSU 938 - Research Center of Saint Antoine

UNKNOWN

lead

Assistance Publique - Hôpitaux de Paris

OTHER