An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

March 30, 2022

Primary Completion Date

April 1, 2023

Study Completion Date

April 1, 2023

Conditions
Severe Hepatic Impairment
Interventions
DRUG

aumolertinib

A single dose of 55-mg EQ143 tablet will be administered in the morning on Day 1, and participants will remain for 5 days (4 nights) in the study center for collection of blood samples and safety monitoring. Participants will attend outpatient follow-up visits on Days 5, 6, 8, and 9 for additional blood sampling and safety assessments.

Trial Locations (3)

33705

Global Clinical Professionals, St. Petersburg

78215

Texas Liver Institute, San Antonio

90017

American Institute Research, Los Angeles

Sponsors
All Listed Sponsors
lead

EQRx International, Inc.

INDUSTRY