Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI

NACompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

March 1, 2024

Study Completion Date

March 1, 2024

Conditions
Cardiovascular Abnormalities
Interventions
OTHER

Ultrasound

Participants will have a routine ultrasound of the heart (echocardiogram) before the procedure. During this test we will take a few extra measurements, this will not add any significant time to the scan

PROCEDURE

Catheters

During the TAVI procedure 3 catheters (tubes) will be inserted into the blood vessels at the top of the participants legs as per normal standard care (there will be no extra skin punctures as part of the study).

PROCEDURE

Soft study wire

Participants will have a soft study wire inserted to measure the pressure in the left ventricle. This step is in addition to standard care.

RADIATION

X-ray

Participants will have chests x-ray when the soft study wire is inserted.

DRUG

Dobutamine

Participants will be given a low dose infusion of dobutamine, to make the heart pump quicker and more vigorously.. This will last for approximately 5 minutes

Trial Locations (1)

WV10 0QP

The Royal Wolverhampton NHS Trust, Wolverhampton

All Listed Sponsors
lead

The Royal Wolverhampton Hospitals NHS Trust

OTHER_GOV