NCT05191940View on ClinicalTrials.gov

Radiotherapy for Locally Advanced Pancreatic Carcinomas (Phase II Trial)

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 16, 2022

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Pancreas Cancer
Interventions
RADIATION

Particle-therapy using protons or carbon ions

According to the radiation plan (between 25 and a maximum of 40 Gy). Planning Target Volume 1 : 25 Gy (Relative Biological Effectiveness) in 5 fractions of 5 Gy (Relative Biological Effectiveness) Planning Target Volume 2 : A simultaneous integrated boost (SIB) will be delivered to the Planning Target Volume 2: 40 Gy (Relative Biological Effectiveness) in 5 fractions of 8 Gy (Relative Biological Effectiveness).

DIAGNOSTIC_TEST

Blood sampling

Evaluation before treatment-start, after treatment and follow-up period.

DIAGNOSTIC_TEST

Magnetic resonance imaging

For treatment planning as well as for follow-up radiological tumor assessment.

DIAGNOSTIC_TEST

Computertomography

For treatment planning as well as for follow-up radiological tumor assessment.

DIAGNOSTIC_TEST

18-F-FluorDesoxyGlukose Positron Emission Tomography-Computer Tomography (18F-FDG-PET-CT)

For treatment planning as well as for follow-up radiological tumor assessment.

Trial Locations (1)

2700

RECRUITING

EBG MedAustron GmbH, Wiener Neustadt

All Listed Sponsors
lead

EBG MedAustron GmbH

INDUSTRY