56
Participants
Start Date
August 1, 2022
Primary Completion Date
February 26, 2025
Study Completion Date
November 26, 2025
Treatment 'discontinuation of antidepressant medication'
Pharmacological intervention: Participants will discontinue their antidepressant medication.
Treatment 'continuation of antidepressant medication'
Pharmacological intervention: Participants will remain on their antidepressant medication.
Expectation 'high'
Psychological intervention: Participants' expectations will be manipulated by varying verbal instructions using the open-hidden paradigm. Within the open trial arms, participants will receive full information about their treatment (i.e., high expectation). expectation).
Expectation 'moderate'
Psychological intervention: Participants' expectations will be manipulated by varying verbal instructions using the open-hidden paradigm. Within the hidden trial arms, participants will be informed about a 50% chance of discontinuing versus remaining on their antidepressant medication (i.e., moderate expectation).
University Medical Center Hamburg-Eppendorf, Hamburg
Philipps University Marburg
OTHER
Helmut Schmidt University
OTHER
University Hospital, Essen
OTHER
Universitätsklinikum Hamburg-Eppendorf
OTHER