Evaluation of Photodynamic Therapy in Treatment of Peri-implantitis

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2016

Study Completion Date

May 31, 2017

Conditions
Peri-Implantitis
Interventions
PROCEDURE

Photodynamic (PDT) group

Mucoperiostal buccal and lingual incisions were made using a surgical blade under local anaesthesia. Full-thickness mucoperiosteal flaps were elevated buccally and lingually. In the photodynamic (PDT) group, after careful removal of granulation tissue and mechanical debridement of the implant surface, decontamination of implant surfaces and peri-implant tissues was performed using the photodynamic therapy, PDT (HELBO, Photodynamic Systems GmbH, Wels, Austria). The implant surface and the surrounding tissue were exposed to the laser light by means of fibres (HELBO ® TheraLite Laser HELBO ® 2D Spot Probe; bredent medical GmbH \& Co KG) for the 30s/spot, which operates on the wavelength of 660 nm and irradiance of 100 Mw. Bone augmentation and bio-resorbable membrane were applied in peri-implant defects using the bovine bone substitute and collagen membrane (Bio -Oss and Bio Guide, GeistlichPharma; Dembone). The mucoperiosteal flaps were repositioned and sutured.

PROCEDURE

Chlorhexidine (CHX) group

Mucoperiostal buccal and lingual incisions were made using a surgical blade under local anaesthesia. Full-thickness mucoperiosteal flaps were elevated buccally and lingually. In the chlorhexidine (CHX) group, after careful removal of granulation tissue and mechanical debridement of the implant surface 1% gel of chlorhexidine (Chlorhexamed® - Direkt) was applied on the implant surface for one minute and irrigated for 1 min by saline. Bone augmentation and bio-resorbable membrane were applied in peri-implant defects using the bovine bone substitute and collagen membrane (Bio -Oss and Bio Guide, GeistlichPharma; Dembone). The mucoperiosteal flaps were repositioned and sutured.

Trial Locations (1)

11000

Department of Periodontal and Oral Mucosa Diseases, Belgrade

All Listed Sponsors
collaborator

Military Medical Academy, Bulgaria

OTHER

collaborator

Bredent Medical, Helbo

OTHER

lead

University of Belgrade

OTHER

NCT05187663 - Evaluation of Photodynamic Therapy in Treatment of Peri-implantitis | Biotech Hunter | Biotech Hunter