Photodynamic Therapy for COVID-19 Prevention

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

December 20, 2021

Primary Completion Date

April 30, 2022

Study Completion Date

May 30, 2022

Conditions
COVID-19 Respiratory InfectionSARS-CoV-2 Acute Respiratory Disease
Interventions
DEVICE

Nasal Photodisinfection

The procedure is initiated by swabbing the Formulation Applicator, pre-saturated with photosensitizer formulation, inside the patient's nares. The operator then connects the Nasal Light Illuminator (NLI) to the Light Source and inserts the NLIs into the patient's nostrils. The Light Source is turned on, and a 4-minute illumination cycle provides two channels of diffused red light (one for each nostril) to activate the applied formulation. Illumination stops automatically upon completion of the 4-minute cycle. The process is then repeated using two new Formulation Applicators to ensure full disinfection coverage.

DEVICE

Sham Comparator: Control

Patients who are SARS-CoV-2 positive whose PCR levels are followed but no active intervention will be done. Saline will be used in their nose and the light device will be inserted but not turned on. Patient will be wearing light protecting glasses.

Trial Locations (1)

31008

Clinica Universidad de Navarra, Pamplona

Sponsors
All Listed Sponsors
collaborator

University of Navarra

OTHER

lead

Ondine Biomedical Inc.

INDUSTRY