A Multicenter, Randomized Controlled, Phase II Clinical Study of First-line Chemotherapy and Camrelizumab With or Without Radiotherapy in the Treatment of Oligometastatic Esophageal Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

118

Participants

Timeline

Start Date

December 31, 2021

Primary Completion Date

December 1, 2023

Study Completion Date

December 1, 2025

Conditions
Esophageal Cancer
Interventions
RADIATION

Radiotherapy group

Stereotactic body radiotherapy (SBRT, 8Gy/time, 3 -5 times, if other segmentation schemes are used, recommend BED10 \>60Gy) or conventional fractional radiotherapy (parts that are not suitable for SBRT, the total dose is more than 30Gy); the primary lesion should be treated with conventional fractional radiotherapy with a dose of 4000cGy or more;

DRUG

Camrelizumab

4 cycles for combined therapy. Camrelizumab maintenance.

DRUG

Chemotherapy

4 cycles for combined therapy.

Trial Locations (1)

310022

Zhejiang Cancer Hospital, Hangzhou

All Listed Sponsors
collaborator

Zhejiang Provincial People's Hospital

OTHER

collaborator

The First Affiliated Hospital of Wenzhou Medical Univercity

UNKNOWN

collaborator

Jinhua Municipal Central Hospital

OTHER

collaborator

Lishui Municipal Central Hospital

OTHER_GOV

collaborator

The Affiliated People's hospital of Ningbo Univercity

OTHER

collaborator

Huizhou Municipal Central Hospital

OTHER

collaborator

People's Hospital of Quzhou

OTHER

collaborator

Sun Yet-sen Cancer Center

UNKNOWN

lead

Zhejiang Cancer Hospital

OTHER