Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas

PHASE2RecruitingINTERVENTIONAL
Enrollment

119

Participants

Timeline

Start Date

April 25, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Soft Tissue Sarcoma AdultAdvanced Soft-tissue SarcomaEwing SarcomaOsteosarcomaUndifferentiated Pleomorphic Sarcoma
Interventions
DRUG

Association of pembrolizumab + cabozantinib

"A treatment cycle consists of 3 weeks. Pembrolizumab will be administered intraveinously on day 1 every 3 weeks (200 mg).~Cabozantinib will be administered per os, once daily (40 mg), and given on a continuous basis."

Trial Locations (10)

13009

RECRUITING

Institut Paoli Calmettes, Marseille

13385

RECRUITING

Hôpital La Timone, Marseille

21079

RECRUITING

Centre Georges François Leclerc, Dijon

31059

NOT_YET_RECRUITING

IUCT Oncopole, Toulouse

33076

RECRUITING

Institut Bergonie, Bordeaux

44805

RECRUITING

Institut de Cancérologie de l'Ouest - Site René Gauducheau, Saint-Herblain

59020

NOT_YET_RECRUITING

Centre Oscar Lambret, Lille

69008

NOT_YET_RECRUITING

Centre Leon Berard, Lyon

75248

NOT_YET_RECRUITING

Institut Curie, Paris

94805

RECRUITING

Institut Gustave Roussy, Villejuif

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Ipsen

INDUSTRY

collaborator

MSD France

INDUSTRY

lead

Institut Bergonié

OTHER