NCT05181527View on ClinicalTrials.gov

Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder

PHASE4CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 10, 2022

Primary Completion Date

September 30, 2023

Study Completion Date

November 30, 2023

Conditions
Major Depressive Disorder
Interventions
DRUG

Selective Serotonin Reuptake Inhibitors

Patients in both the study arms will receive SSRI for 8 weeks.

DRUG

Dextromethorphan

Patients in the test group will get Dextromethorphan 30 mg once daily orally as an add-on to ongoing SSRI treatment for 8 weeks.

DRUG

Placebo

Patients in the control group will get placebo tablet once daily orally as an add-on to ongoing SSRI treatment for 8 weeks.

Trial Locations (1)

751019

All India Institute of Medical Sciences (AIIMS), Bhubaneswar

All Listed Sponsors
lead

All India Institute of Medical Sciences, Bhubaneswar

OTHER