A Phase 1/2 Study of BA3071 in Patients With Solid Tumors

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

August 3, 2022

Primary Completion Date

March 19, 2025

Study Completion Date

June 30, 2026

Conditions
NSCLCMelanoma
Interventions
BIOLOGICAL

BA3071

Conditionally active biologic (CAB) antibody that binds to CTLA-4

BIOLOGICAL

Nivolumab

Humanized, immunoglobulin G4 (IgG4)-variant mAb against PD-1

BIOLOGICAL

Pembrolizumab

Humanized antibody, immunoglobulin G4, with a variable region against the human PD-1 receptor

DRUG

Pemetrexed (Alimta)

pemetrexed with either cisplatin or carboplatin

Trial Locations (12)

2228

Cancer Care Foundation, Miranda

2640

Border Medical Oncology Research Unit at Albury Wodonga Regional Cancer Centre, Albury

5000

Cancer Research South Australia, Adelaide

10029

Icahn School of Medicine at Mt. Sinai, New York

30318

Piedmont West, Atlanta

44106

University Hospitals Cleveland Medical Center, Cleveland

46311

Northwest Cancer Centers, Dyer

84112

University of Utah Huntsman Cancer Institute, Salt Lake City

90025

The Angeles Clinic and Research Institute, Los Angeles

90033

USC Norris Comprehensive Cancer Center, Los Angeles

97213

Providence Cancer Institute, Portland

07960

Morristown Medical Center/Atlantic Health System, Morristown

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BioAtla, Inc.

INDUSTRY