Spinal Cord Stimulation and Respiration After Injury

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 31, 2021

Primary Completion Date

February 28, 2026

Study Completion Date

December 31, 2030

Conditions
Spinal Cord InjuriesSpinal Cord StimulationBreathing ExercisesRehabilitation
Interventions
DEVICE

Spinal Cord Epidural Stimulation

Spinal Cord Epidural Stimulation (scES) will be administered by a multi-electrode array (5-6-5 SpecifyTM electrode, MEDTRONIC, Minneapolis, MN, USA) previously implanted in the epidural space over the dorsum of the spinal cord.

OTHER

Respiratory Training

Standard threshold Positive Expiratory Pressure Device and standard threshold Inspiratory Muscle Trainer (Respironics Inc., Cedar Grove, NJ) assembled together will be used for respiratory training sessions to complete eighty 45-minute sessions during 16 weeks. The participants will be instructed to perform inspiratory and expiratory efforts against a pressure treshold load.

Trial Locations (1)

40202

RECRUITING

Frazier Rehabilitation and Neuroscience Institute, Louisville

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Louisville

OTHER