Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer

PHASE2TerminatedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

January 17, 2022

Primary Completion Date

April 5, 2023

Study Completion Date

April 5, 2023

Conditions
Metastatic Castration-resistant Prostate CancerProstate Cancer
Interventions
DRUG

SRF617

SRF617 is a fully human antibody designed to inhibit the enzymatic activity of CD39.

DRUG

etrumadenant

Etrumadenant is an A2aR and A2bR antagonist.

DRUG

zimberelimab

Zimberelimab is a fully human anti-PD-1 monoclonal antibody.

Trial Locations (9)

33136

University of Miami - Sylvester Comprehensive Cancer Center, Miami

48109

University of Michigan Health System, Ann Arbor

75390

UT Southwestern, Dallas

78229

START South Texas Accelerated Research Therapeutics, LLC, San Antonio

84119

Comprehensive Cancer Centers of Nevada, Las Vegas

START Mountain Region, Utah Cancer Specialists, West Valley City

98109

Fred Hutchinson Cancer Research Center, Seattle

V5Z 4E6

BC Cancer - The Vancouver Centre, Vancouver

H2X 0A9

Université de Montreal - Centre de Recherche du Centre Hospitalier de L'Université de Montreal (CRCHUM), Montreal

All Listed Sponsors
collaborator

Arcus Biosciences, Inc.

INDUSTRY

collaborator

Surface Oncology

INDUSTRY

lead

Coherus Oncology, Inc.

INDUSTRY